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CompareM2

GitHub Actions Workflow Status Bioconda downloads conda build Docker Pulls Documentation Status

!!! info If you're looking for CompareM, a tool that calculates AAI and codon usage, please follow this link: github.com/donovan-h-parks/CompareM

🧬 CompareM2 is a genomes-to-report pipeline. It accepts prokaryotic (bacterial and archaeal) genomic assemblies and compares them in many different ways.

🦠 Being designed to analyze assemblies of both isolates and metagenomes (MAGs), it is useful for anyone working with microbial genomics.

💾 Installing CompareM2 on your system gives you access to many powerful state-of-the-art tools for analysis of prokaryotic genomes which will accelerate your research. It is easy to use and can be used by non-bioinformaticians.

👩‍🔬 CompareM2 integrates several analyses that yield scientific results about genomic assemblies on several levels: Quality control, annotation, function and species calling as well as comparative analyses like computation of core/pan genomes and phylogenetics.

🐍 CompareM2 works by calling a Snakemake workflow that can be easily modified to use different parameters for the underlying tools.

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📙 Central results are dynamically integrated in a compact portable report .html-document. It can be browsed in any web browser and can be easily shared as a single file. This report is generated even if some jobs in the pipeline fail. See examples.

🧑‍💻 CompareM2 can be run either on a local workstation (recommended >= 64GiB RAM), or a HPC (high performance computing) cluster. Both Apptainer/Singularity/Docker images and conda environment definitions are available for all dependent software to run.

The comprehensive documentation is available at CompareM2.readthedocs.io.


CompareM2 genomes-to-report pipeline. Copyright (C) 2024 C. M. Kobel GNU GPL v3