Smart-seq2 full length RNA-seq data

[seongguheo]

Dear Author,

Thank you for the wonderful tool.
I wonder if it can analysis Smart-seq2 full length single cell RNA-seq data as well.
If it can, what should be come for --tech ?

Best
Heo

[nghiavtr]

Dear @seongguheo,

Thank you for your interesting in our isoform quantification tool.

Scasa is designed for prime-biased single-cell RNA-seq data. For the full-length Smart-seq2, you can use another tool from our group, XAEM (https://www.meb.ki.se/sites/biostatwiki/xaem/) that it has demonstrated well performance for both bulk RNA-seq and full-length Smart-seq2 data in its publication (https://academic.oup.com/bioinformatics/article/36/3/805/5545974)

Drop me a line if you have any issues with either Scasa or XAEM.

Best,
Nghia