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GO:0000030 | mannosyltransferase activity | IBA with PTN001997630  #5292

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ValWood opened this issue Jun 19, 2024 · 4 comments
Closed

GO:0000030 | mannosyltransferase activity | IBA with PTN001997630  #5292

ValWood opened this issue Jun 19, 2024 · 4 comments
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@ValWood
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ValWood commented Jun 19, 2024

  • PTHR ID & PTN node:

GO:0000030 | mannosyltransferase activity | IBA with PTN001997630 , S000005102 | contributes_to | GO_REF:0000033

  • Sequences with problematic annotation (ID + gene/protein name):

https://www.pombase.org/gene/SPAC167.09 pga1

  • Type of Issue: Erroneous source or erroneous propagation, or other issue

Incorrect annotation.
pga1 is a subunit of
GO:0120097 | glycosylphosphatidylinositol-mannosyltransferase II complex

GPI18 appears to be the mannosyltransferase subunit
pga1 appears to be essential regulatory subunit

@edwong57

  • Add the label 'high priority' if needed. Generally high priority issues affect a lot of proteins, and annotations are incorrect (as opposed to just imprecise).
@edwong57
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@ValWood Is there anything that I need to do?

@ValWood
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ValWood commented Jun 19, 2024

Hi Sorry yes, the annotation is to mannosyltransferase, but this is the regulatory subunit, not the catalytic subunit.
v

@edwong57
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@ValWood Do you have a reference I can look at for changing the annotation? I have been looking at the ones associated with our current annotations in our database, and I am not seeing what you are. If you already have a reference, that'd be helpful.

@marcfeuermann
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This one was annotated as contributes-to. Annotation remove. I close this one as discussion is redundant to
#5293

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