CompPlots.ipynb

{
 "cells": [
  {
   "cell_type": "code",
   "execution_count": 1,
   "metadata": {},
   "outputs": [],
   "source": [
    "using Pkg\n",
    "Pkg.instantiate()\n",
    "using TAMode\n",
    "using Plots\n",
    "using StaticArrays\n",
    "using LinearAlgebra"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 2,
   "metadata": {},
   "outputs": [
    {
     "output_type": "execute_result",
     "data": {
      "text/plain": [
       "Summary Statistics\n",
       " \u001b[1m    parameters \u001b[0m \u001b[1m    mean \u001b[0m \u001b[1m     std \u001b[0m \u001b[1m naive_se \u001b[0m \u001b[1m    mcse \u001b[0m \u001b[1m     ess \u001b[0m \u001b[1m    rhat \u001b[0m\n",
       " \u001b[90m        Symbol \u001b[0m \u001b[90m Float64 \u001b[0m \u001b[90m Float64 \u001b[0m \u001b[90m  Float64 \u001b[0m \u001b[90m Float64 \u001b[0m \u001b[90m Float64 \u001b[0m \u001b[90m Float64 \u001b[0m\n",
       "\n",
       "        AXLexpr   33.7065    3.1431     0.1988    1.4321    5.4480    1.1274\n",
       "         Ig2rev    0.0329    0.0635     0.0040    0.0267    5.0778    1.1228\n",
       "         gasCur    0.1279    0.0902     0.0057    0.0332    7.2285    1.0841\n",
       "    internalize    0.0473    0.0105     0.0007    0.0031   11.1634    1.0478\n",
       "           kDeg    0.0212    0.0048     0.0003    0.0026    4.6812    1.1543\n",
       "           kRec    0.1071    0.0119     0.0008    0.0031   18.7062    0.9973\n",
       "  pYinternalize    1.0975    0.1366     0.0086    0.0163    9.8463    1.0011\n",
       "          scale    0.0212    0.0066     0.0004    0.0034    5.1126    1.1014\n",
       "      scaleSurf    0.0002    0.0002     0.0000    0.0001    5.4211    1.1160\n",
       "          sortF    0.6591    0.1741     0.0110    0.1128    2.5145    1.3458\n",
       "           xFwd    0.0008    0.0030     0.0002    0.0010    8.8701    1.0646\n"
      ]
     },
     "metadata": {},
     "execution_count": 2
    }
   ],
   "source": [
    "using MCMCChains\n",
    "chn = read(\"chain-file-10_1.jls\", Chains)\n",
    "summarize(chn)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "metadata": {},
   "outputs": [],
   "source": [
    "xFwd = get(chn, :xFwd)[1];\n",
    "Ig2rev = get(chn, :Ig2rev)[1];"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 4,
   "metadata": {},
   "outputs": [],
   "source": [
    "dif = 0.1\n",
    "gasPart = 10\n",
    "gasCur = 0.01\n",
    "AXL = 15.5\n",
    "MerTK = 55\n",
    "Tyro3 = 3.7\n",
    "CompParams = vcat(dif, gasPart, gasCur, xFwd[1], AXL, MerTK, Tyro3, Ig2rev[1], [1.0, 1.0, 1.8, 100.0]);\n",
    "tps = @SVector Float64[0.01, 0.1, 1];\n",
    "r = 1:100;"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 5,
   "metadata": {},
   "outputs": [
    {
     "output_type": "execute_result",
     "data": {
      "text/plain": [
       "3×3×100 Array{Float64,3}:\n",
       "[:, :, 1] =\n",
       " 2.122e-314    2.122e-314    1.04397e-315\n",
       " 4.89231e-316  1.00056e-315  1.00056e-315\n",
       " 6.36599e-314  2.122e-314    2.122e-314\n",
       "\n",
       "[:, :, 2] =\n",
       " 1.04397e-315  2.122e-314    1.52993e-308\n",
       " 1.09242e-315  7.31515e-316  6.0147e-316\n",
       " 6.36599e-314  6.36599e-314  6.36599e-314\n",
       "\n",
       "[:, :, 3] =\n",
       " 2.122e-314    2.122e-314    4.03179e-313\n",
       " 1.06673e-315  1.00056e-315  9.88379e-316\n",
       " 6.36599e-314  2.122e-314    6.36599e-314\n",
       "\n",
       "...\n",
       "\n",
       "[:, :, 98] =\n",
       " 2.122e-314  0.0           9.54e-322\n",
       " 0.0         9.97009e-316  1.00059e-315\n",
       " 0.0         0.0           6.9161e-310\n",
       "\n",
       "[:, :, 99] =\n",
       " 1.00059e-315  2.122e-314  0.0\n",
       " 1.69998e-316  0.0         9.96997e-316\n",
       " 0.0           0.0         0.0\n",
       "\n",
       "[:, :, 100] =\n",
       " 4.8e-322      1.00059e-315  2.122e-314\n",
       " 1.00059e-315  1.69998e-316  0.0\n",
       " 6.9161e-310   0.0           0.0"
      ]
     },
     "metadata": {},
     "execution_count": 5
    }
   ],
   "source": [
    "pp = TAMode.compParamm(CompParams)\n",
    "pY = TAMode.compTAM(tps, pp)\n",
    "cplot = Array{Float64}(undef, length(tps), length(tps), 100)\n",
    "cplot_total = Array{Float64}(undef, length(tps), length(tps), 100)\n",
    "total_normalized = Array{Float64}(undef, length(tps), length(tps), 100)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 7,
   "metadata": {},
   "outputs": [],
   "source": [
    "for rr = 1:100\n",
    "    for t = 1:length(tps)\n",
    "        pYdata = view(pY, t, :, rr)\n",
    "        cplot[t, :, rr] .= dot(pYdata, TAMode.pYc)\n",
    "        cplot_total[t, :, rr] .= dot(pYdata, TAMode.totalC)\n",
    "        total_normalized[t, :, rr] = cplot[t, :, rr] ./ cplot_total[t, :, rr]\n",
    "    end\n",
    "end"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 8,
   "metadata": {},
   "outputs": [
    {
     "output_type": "execute_result",
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     },
     "metadata": {},
     "execution_count": 8
    }
   ],
   "source": [
    "plotpY = view(cplot, 1, 1, :)\n",
    "plot(r, plotpY, title = \"Total Receptor pY\", label = tps[1], lw = 3)\n",
    "if length(tps) > 1\n",
    "    for tt = 2:length(tps)\n",
    "        plotpY = view(cplot, tt, tt, :)\n",
    "        plot!(r, plotpY, label = tps[tt], lw = 3)\n",
    "    end\n",
    "end\n",
    "xlabel!(\"Radius\")\n",
    "ylabel!(\"pY\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 9,
   "metadata": {},
   "outputs": [
    {
     "output_type": "execute_result",
     "data": {
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     },
     "metadata": {},
     "execution_count": 9
    }
   ],
   "source": [
    "plotpY = view(total_normalized, 1, 1, :)\n",
    "plot(r, plotpY, title = \"Normalized pY\", label = tps[1], lw = 3)\n",
    "if length(tps) > 1\n",
    "    for tt = 2:length(tps)\n",
    "        plotpY = view(total_normalized, tt, tt, :)\n",
    "        plot!(r, plotpY, label = tps[tt], lw = 3)\n",
    "    end\n",
    "end\n",
    "xlabel!(\"Radius\")\n",
    "ylabel!(\"pY\")"
   ]
  }
 ],
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